Dr C Maclay Dr C Maclay

Lifestyle Medicine: A Necessary Bridge in a System Built for Crisis, Not Prevention

I support this movement not only because it restores agency to both doctor and patient, but because it acknowledges what many avoid: the mounting burden of environmental toxicity, poor urban design, ultra-processed foods, and social disconnection as key contributors to modern disease and suffering. These factors impose not only human costs but enormous strain on public health budgets.

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Dr C Maclay Dr C Maclay

Can the Media help society resolve problems?

Today, I can hear the headline and tell you the outlet. I can see the spin and name the editor. Tell me the reporter, and I’ll tell you the narrative. What we consume as “news” is often preloaded with opinion, curated to echo the worldview of its audience. Objectivity has become quaint; tribalism sells better.

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Dr C Maclay Dr C Maclay

Healthcare Systems, Regulation, and the Big Picture

The health outcomes of a population reflect the efficacy of the public health systems and regulatory structures. While incoming leaders, including the new CEO of AHPRA, acknowledge challenges in implementation and resourcing, I’m not sure we’ve fully recognised that systems errors — not just surface-level or budget-driven issues — may be at play. If these deeper structural issues remain unaddressed, it becomes harder to fix the symptomatic problems that we all see.

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Dr C Maclay Dr C Maclay

Myostatin: The Muscle Brake We May One Day Release - but not yet

In early human trials, some agents showed promise in increasing muscle volume. For example, ACE-083, an intramuscular myostatin inhibitor, led to localized muscle growth in patients with neuromuscular disease. Other agents like domagrozumab and taldefgrobep alfa showed similar results—more muscle, better biomarkers. But here's the catch.,,,,,,,

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Dr C Maclay Dr C Maclay

AI can end the narrative monopoly in Healthcare.

the Evidence-Based Medicine (EBM) and Clinical Practice Guidelines (CPG) framework has produced a narrow, top-down model of care. While this system has undoubtedly improved consistency and documentation, it has also coincided with a healthcare landscape increasingly shaped by corporate priorities, not patient outcomes.

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Dr C Maclay Dr C Maclay

Ignoring Wellness Is Unjustified

For healthcare providers, recognising this need is central to modern patient care. For patients, engaging in wellness strategies is no longer optional—it is a responsible, science-aligned response to modern life. Protocols can be developed and delivered at every level of care.

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Dr C Maclay Dr C Maclay

Doing nothing is no longer an option.

To simply wait for disease to declare itself is to miss the entire point of modern longevity and functional medicine. We must now become proactive custodians of biology — identifying early signs of cellular dysfunction, supporting detoxification pathways, and improving the body’s internal communication networks (paracrine, endocrine, and beyond).

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Dr C Maclay Dr C Maclay

Too TAME?

Metformin is safe, cheap, already approved for diabetes. It prevents chronic disease and even ageing. Yet it cannot overcome the regulatory barriers to approval for this indication. What does this say about regulatory approval?

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Dr C Maclay Dr C Maclay

The big answers to health and wellness face barriers to implementation.

Emerging therapies, often used in integrative, functional, or boutique clinical settings, are targeting these mechanisms. Therapies that include nutritional and peptide interventions, microbiome modulation, detoxification protocols, precision supplementation, and regenerative strategies are showing remarkable promise. But they remain largely excluded from mainstream care.

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Dr C Maclay Dr C Maclay

The CHRONIC DISEASE Epidemic

Despite this health landscape, governments and public health agencies continue to pour trillions of dollars annually into healthcare - largely into the management of disease, not its prevention or cure…..

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Dr C Maclay Dr C Maclay

Process Over Outcomes

A system focused on process gets good processes. A system focused on outcomes gets good outcomes.

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Dr C Maclay Dr C Maclay

Why NAD+ Levels Matter

….Animal and early human studies suggest NAD+ restoration can improve metabolism, reduce neurodegeneration, and enhance cardiovascular health. Clinical trials are ongoing to explore NAD+ precursors' effects on aging, chronic diseases, and overall healthspan........…

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Dr C Maclay Dr C Maclay

Gut Flora - Essential for Health and Wellbeing.

….gut flora is indispensable for our health and survival. Many essential substances, like certain vitamins, can only be produced by these microorganisms. This also explains why some chemicals, deemed harmless to humans because they don’t target our proteins, can still profoundly harm us by disrupting the gut flora. These microorganisms interact with dietary information, signalling our immune and neurological systems in response........…

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Dr C Maclay Dr C Maclay

Bias Feedback Loops?: Drug Approvals and Clinical Guidelines.

….Guidelines are typically built on evidence from studies published in peer-reviewed journals, and these studies are overwhelmingly funded by pharmaceutical companies. Since the approval process prioritises interventions that fit the pharmaceutical model—patentable, profitable, and quantifiable—these therapies dominate the body of evidence.......…

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